Done with my pharmacology sendup/mock today. Posting the Short Essay Question part here for medical students from other colleges in Pakistan.
Q-1 What are the various methods employed for prolonging actions of certain drugs?
Describe different types of Drug Antagonism. Give one example for each type. (4 , 5)
Q-2 Describe mechanism of benefitial effect of
a) B-blockers in hypertension
b) Quinidine in ventricular arrythmias. (4, 5)
Q-3 What is the relation of mechanism of action of following to their clinical response?
a) Pro-kinetic effect of cisapridine
b) Anti-depressant action of Impipramine. (4,5)
Q-4 What are the different ways by which drugs can stabalize neurnonal cell membranes and inhibit spread of seizure activity in epilepsy? (9)
Q-5 Name Disease Modifying Drugs used in Rheumatoid Arthritis.
Decribe precisely the mechanism by which Methotrexate helps in suppressing disease process. (4,5)
Q-6 Name antiplatelet agents
What are merits and demerits of COX-2 selective inhibitors compared to Aspirin.
Q-7 Name Opiods that interact primarily with mu-receptor. What actions of morphine are ascribed to mu receptors activation. (4,5)
a) Drugs that inhibit folic acid synthesie in bacterial and protozoal systems.
b) Drugs that have malarial efficacy in grma negative rods.
c) Uses and adverse effects of Metronidazole. (3,3,3)
Q.-9 Give cellular target for the action of following
a) Anti-gout effect of Allopurinol
b) Anti-Psychotic action of Clozapine
c) Anti-coagulant effect of Heparin (3,3,3)
Q.10 Write short notes on
a) Insulin secretagogues
b) Ketamine (4,5)